Exosomes : Cell Garbage Can , Therapeutic Carrier , or Trojan Horse ? Running title :
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Exosomes: cell garbage can, therapeutic carrier, or trojan horse?
Ottawa Hospi pi pita ta tal l l Re Re Rese se s ar ar arch ch I I Ins ns nstitu tu tute te t
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In multicellular organisms, cells communicate with each other via extracellular molecules such as nucleotides, lipids, short peptides, or proteins. These molecules are released in the extracellular space to bind to receptors on other cells, thus modifying intracellular signaling in the recipient cells. In addition to these single molecules, cells also release in their extracellular environment ...
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Intercellular communication via cell-released vesicles is a very important process for both normal and tumor cells. Cell communication may involve exosomes, small vesicles of endocytic origin that are released by all types of cells and are found in abundance in body fluids, including blood, saliva, urine, and breast milk. Exosomes have been shown to carry lipids, proteins, mRNAs, non-coding RNA...
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